Angela Zhou

Angela Zhou

Zhou
Visiting Assistant Professor
Position Type 
Faculty
Service 
2016 - Present
All Affiliations 

Overview

Biography 

B.S. in Life Sciences from Fudan University, Shanghai, China, 2002

Ph.D. in Molecular Pharmacology and Toxicology from University of Southern California, Los Angeles, CA 2006

Postdoctoral Research Fellow in Cell Biology from Johns Hopkins Medical School, Baltimore, MD 2006-2009

Postdoctoral Research Fellow in Cancer Biology from Harvard Medical School/Dana Farber Cancer Institute, Boston, MA 2009-2011

Learning & Teaching

Courses 

Molecular Biology and Unicellular Life, Cancer Biology

Research

Details 

I am interested in this cellular event, because cytokinesis is closely related to cancer development. If the cell fails cytokinesis, it may develop into cancer cells. At the same time, small molecules that can inhibit cytokinesis may also be potential anti-cancer drugs.

Microtubules are a type of cytoskeleton. During mitosis and cytokinesis, microtubules provide numerous functions, including capturing and separating the chromosome and delivering the cues that coordinate cell shape changes. During postdoc training, I found 14-3-3 as a novel cytokinesis related gene was able to facilitate cytokinesis by stabilizing microtubules and regulates the cell cortical tension. Currently interested in discovering the more unique roles of 14-3-3 in the regulation of cytokinesis using Dictyostelium cells and many cancer cell lines as research models.