This course expands upon concepts in molecular structure and behavior presented in CHEM 131 and CHEM 132 and applies them to the systematic investigation of the reactivity of organic molecules. Students will explore the transformation and reaction chemistry of organic functional groups, including alcohols, aromatics, aldehydes, ketones, carboxylic acids, and their derivatives. Reactions are explored with an emphasis on the mechanism of reactivity, and in the context of organic synthesis with a focus on the art of retrosynthetic analysis for complex targets. Laboratory experiments are selected to introduce techniques for the synthesis, purification, and analysis of organic compounds discussed in class. Offered in the fall only. Three class periods and one laboratory weekly. Safety glasses required. Prerequisite: CHEM 132.